Pain：医书可有效预防偏头痛复发和加重

新闻记者从日前在京召开的2011年方剂国际间研讨会上发觉，首都医科大学附属北京医学医院方剂中心经临床科学研究证实，习惯的医学方剂疗法可适当传染病癫痫的复发和更为情况严重。相关科学研究专著近日发表在国际间有名医学期刊《咳嗽》上，带进近现代大陆首篇发表于该杂志的临床科学研究专著。该文还被国际间闻名医学遗传学的机构 Faculty of 1000 medicine（千名微遗传学家）收录于。

据了解，作为临床常见病之一，癫痫发病更高，且危害情况严重。目前为止，我国18岁~65岁人群的癫痫丙型肝炎更高达9.3%，且有大幅度增大急遽。方剂疗法咳嗽在近现代并未有数千年的历史背景。北京医学医院方剂中心自2004年分设咳嗽专家门诊，开展了基于“金针王为乐亭”、曾三度更高手贺普仁等多位有名方剂学家治痛经验的咳嗽科学研究。

据该中心主任王为麟鹏介绍，该项目实行单盲、双三维、结果表明的形式，在国内5家医院的方剂科共招募140名无先兆癫痫病患，随机分为两第一组，分别为疗法第一组（方剂加口服）和对照第一组（假针加氟桂利嗪）。两第一组病患每周方剂疗法3次，每晚口服药物。调查结果，4周后，疗法第一组癫痫的适当加重率为59%，对照第一组为40%；疗法第一组咳嗽年数大约减少4.1天，对照第一组大约减少1.9天。16周后，疗法第一组适当加重率为56%，对照第一组为37%；疗法第一组咳嗽年数大约减少 4.1天，对照第一组大约减少2天。

科学研究人员据此认为，方剂可以作为癫痫的传染病复发和更为情况严重的步骤，其治果也优于此前国外的相关科学研究。由于其科学研究步骤的新颖和更进一步，该专著还被国际间闻名医学遗传学的机构“千名科学家”收录于。（生物谷 Bioon.com）

doi:10.1016/j.pain.2011.04.006PMC:PMID:

Efficacy of acupuncture for migraine prophylaxis: A single-blinded, double-dummy, randomized controlled trial

Lin-Peng Wang,Xiao-Zhe Zhang,Jia Guo,Hui-Lin Liu,Yan Zhang,Cun-Zhi Liu,Jing-Hong Yi,Li-Ping Wang,Ji-Ping Zhao,Shan-Shan Li

Summary This multicenter, double-dummy trial suggested that acupuncture was more effective than flunarizine in decreasing days of migraine attacks. Abstract Insufficient clinical trial data were ailable to prove the efficacy of acupuncture for migraine prophylaxis. A multicenter, double-dummy, single-blinded, randomized controlled clinical trial was conducted at the outpatient departments of acupuncture at 5 hospitals in China to evaluate the effectiveness of acupuncture. A total of 140 patients with migraine without aura were recruited and assigned randomly to 2 different groups: the acupuncture group treated with verum acupuncture plus placebo and the control group treated with sham acupuncture plus flunarizine. Treated by acupuncture 3 times per week and drugs every night, patients from both groups were evaluated at week 0 (baseline), week 4, and week 16. The primary outcome was measured by the proportion of responders (defined as the proportion of patients with a reduction of migraine days by at least 50%). The secondary outcome measures included the number of migraine days, visual ogue scale (VAS, 0 to 10cm) for pain, as well as the physical and mental component summary scores of the 36-item short-form health survey (SF-36). The patients in the acupuncture group had better responder rates and fewer migraine days compared with the control group (P.05). The results suggested that acupuncture was more effective than flunarizine in decreasing days of migraine attacks, whereas no significantly differences were found between acupuncture and flunarizine in reduction of pain intensity and improvement of the quality of life.